Elsa and Clive, two young rebellious scientists, defy legal and ethical boundaries and forge ahead with a dangerous experiment: splicing together human and animal DNA to create a new organism. Named ""Dren"", the creature rapidly develops from a deformed female infant into a beautiful but dangerous winged human-chimera, who forges a bond with both of her creators - only to have that bond turn deadly.
Sarah Polley,Adrien Brody,Abigail Chu,Delphine Chaneac,David Hewlett
The sci-fi thriller "Splice" stars Adrien Brody and Sarah Polley as superstar genetic engineers Clive and Elsa, who specialize in splicing together DNA from different animals to create incredible new hybrids. Now they want to use human DNA in a hybrid that could revolutionize science and medicine. But when the pharmaceutical company that funds their research forbids it, Clive and Elsa secretly conduct their own experiments. The result is Dren, an amazing, strangely beautiful creature of uncommon intelligence and an array of unexpected physical developments. And though, at first, Dren exceeds their wildest dreams, she begins to grow and learn at an accelerated rate, and threatens to become their worst nightmare.