Jack and his pals are in a bit of a rut. They've spent 2 decades chasing women and fleeing commitment. They're not quite alcoholic -- more like "alcohol-ish." Jack is about to turn 40, and he's starting to see hidden messages in everyday street signs. Snedden's goal in life is to f@#% his way through the alphabet. Price is 1 drink away from a total meltdown. Victor is a "fretrosexual" -- he never has sex, just worries about it. When a long-lost friend pops up with his beautiful fiancee, the result is a whirl of death, sex and booze -- and Jack realizes he may finally be ready to commit... to the one woman hopelessly out of reach.